Erman Lab Publications
Piepoli, S., Shamloo, B., Bircan, A., Adebali,O., Erman. B. Molecular Biology of SARS-CoV-2 (2020) Turkish Journal of Immunology 8(2):73−88
DOI: 10.25002/tji.2020.1293 (a review on the molecular biology of this terrible virus)
Piepoli, S. Alt, AO. Atilgan,C. Mancini, EJ. and Erman, B. Structural Analysis of the PATZ1 BTB domain homodimer (2020) Acta Crystallographica Section D. Jun 1;76(Pt 6):581-593. DOI: 10.1107/S2059798320005355 (A part of Sofia Piepoli's PhD project. This paper was selected to be featured on the cover page of this crystallagrophy journal. As far as we know, it is the first structural work from Turkey that has been deposited into the PDB database. We continue to crystallize proteins and solve their structures! This was an excellent collaboration between our lab and those of Canan Atilgan and Erika Mancini at Sussex University in the UK)
Kırımtay K, Selçuk E, Kelle D, Erman B, Karabay A. p53 regulates katanin-p60 promoter in HCT 116 cells. Gene. (2020) Feb 15;727:144241. DOI: 10.1016/j.gene.2019.144241 (We contributed to the work of Arzu Karabay at ITU)
Naba, M.N., Tolay, N., Erman, B, Sayi Yazgan, A. The upregulation of PD-L1 expression by doxorubicin in HCT116 colorectal cancer cells accompanied by reduction of miR-140 expression (2019) Turkish Journal of Biology DOI: 10.3906/biy-1909-12 (We contributed to the work of Noel Naba and Ayca Sayi Yazgan at ITU)
Ozyerli-Goknar E, Sur-Erdem I, Seker F, Cingöz A, Kayabolen A, Kahya Z, Uyulur F, Gezen M, Tolay, N, Erman B, Gönen M, Oppermann U, Bagci-Onder T, The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma (2019) Cell Death and Disease, 10, 849. DOI: 10.1038/s41419-019-2107-y (We contributed to the work of Ezgi Ozyerli and Tugba Bagci Onder at Koc University)
Parlar, A., Sayitoglu,EC., Ozkazanc,D., Georgoudaki,A., Pamukcu,C., Aras,M., Josey, BJ., Chrobok,M., Branecki, S., Zahedimaram,P., Ikromzoda,L., Alici,E., Erman,B, Duru,AD, Sutlu, T, Engineering antigen-specific natural killer cells against the melanoma-associated antigen tyrosinase via TCR gene transfer (2019) European Journal of Immunology Aug;49(8):1278-1290. DOI: 10.1002/eji.201948140 (This was an awesome tour de force of biological engineering which resulted in a patent application that is being licenced and will be developed into anti-cancer immunotherapies)
Bonjoch,L. Mur,P. Arnau-Collell,C. Vargas-Parra,G. Shamloo,B. Franch-Expósito, S. Pineda,M. Capellà,G. Erman,B. Castellví-Bel,S. Approaches To Functionally Validate Candidate Genetic Variants Involved In Colorectal Cancer Predisposition (2019) Molecular Aspects of Medicine Special Issue: New insights on the molecular aspects of colorectal cancer. DOI: 10.1016/j.mam.2019.03.004 (A review paper)
Nadernezhad, A. Caliskan, O.S. Topuz,F. Afghah,F. Erman,B. and Koc,B. Nanocomposite Bioinks Based on Agarose and 2D Nanosilicates with Tunable Flow Properties and Bioactivity for 3D Bioprinting (2019) ACS Appl. Bio Mater., 2 (2), pp 796–806 DOI: 10.1021/acsabm.8b00665 (We contributed to the work of Bahattin Koc at Sabanci University)
Etzensperger R, Kadakia T, Tai X, Alag A, Guinter TI, Egawa T, Erman B, Singer A. Identification of lineage-specifying cytokines that signal all CD8+-cytotoxic-lineage-fate 'decisions' in the thymus. (2017) Nat Immunol. Sep 25. doi: 10.1038/ni.3847. (A paper from my post-doctoral laboratory at the NIH)
Deniz E, Erman B. Long noncoding RNA (lincRNA), a new paradigm in gene expression control. Funct Integr Genomics. 2017 May;17(2-3):135-143. doi: 10.1007/s10142-016-0524-x. (A review on these molecules which had just been recently discovered back then)
Keskin, N., Deniz, E., Eryilmaz, J., Un, M., Ersahin, T., Cetin Atalay, R., Sakaguchi, S., Ellmeier, W. and Erman, B. PATZ1 is a DNA damage responsive alternatively spliced heterodimeric transcription factor that inhibits p53 function Molecular and Cellular Biology, 2015 May;35(10):1741-53. doi: 10.1128/MCB.01475-14. (A part of Emre Deniz and Nazli Keskin's PhD projects. Our paper on the molecular mechanism of Patz1 dependent gene transcription is the first output. This project is the major project in our laboratory)
Shamloo, B., and Erman, B. Immune Receptors and Signal Transduction: T and B cell receptors (Immun reseptorler ve sinyal iletimi: T ve B hucre reseptorleri) in Infection Pathogenesis and Immunity (Enfeksiyon Patogenezi ve Bağışıklık), (in Turkish) Ed.s Hakan Abacioglu, Selim Badur and Betigül Öngen (2014)
(A review on T cell receptor signalling in Turkish)
Yilancioglu K, Cokol M, Pastirmaci I, Erman B, Cetiner S. Oxidative Stress Is a Mediator for Increased Lipid Accumulation in a Newly Isolated Dunaliella salina Strain. PLoS ONE 2014 9(3): e91957. doi:10.1371/journal.pone.0091957 (One of the most cited papers with our contribution of staining lipid droplets in algae cells using flow cytometry, thanks Kaan!)
Tai,X., Erman, B., Alag. A., Mu J., Kimura M., Katz G., Guinter, T., McCaughtry, T., Etzensperger, R., Feigenbaum, L., Singer, D.S. and Singer, A. Foxp3 is pro-apoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals. Immunity, 2013, Jun 27;38(6):1116-28. DOI: 10.1016/j.immuni.2013.02.022.
Atasever Arslan B, Erdem-Kuruca S, Karakas Z, Erman B, Ergen A. Effects of micro environmental factors on natural killer activity (NK) of beta thalassemia major patients. Cell Immunol. 2013 Apr;282(2):93-9. DOI: 10.1016/j.cellimm.2013.04.012.
Cevik, S.I., Keskin, N., Deniz, E., Belkaya,S., Ozlu, M.I., Tazebay,U.H., Erman, B. CD81 interacts with the T cell receptor to suppress signaling. PLoS ONE, 2012, 7(11): e50396. DOI:10.1371/journal.pone.0050396 (A part of Isil Cevik's PhD thesis, we performed yeast two hybrid assays and found many molecules that interact with the TCR. We have so many more clones that need to be analyzed).
McCaughtry,T.M., Etzensperger, R., Alag, A., Tai, X., Kurtulus, S., Park, J-H., Grinberg,A. Love, P., Feigenbaum, L., Erman, B., Singer, A. Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus. Journal of Experimental Medicine, 2012, Nov 19;209(12):2263-76. DOI: 10.1084/jem.20121505
Ligons,D.L., Tuncer, C., Linowes, B.A., Akcay, I.M., Kurtulus, S., Deniz, E., Atasever Arslan, B., Cevik, S.I., Keller, H.R., Luckey, M.A., Feigenbaum, L., Möröy,T., Ersahin, T., Atalay, R. and Erman, B., Park, J-H. CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1. Journal of Biological Chemistry. 2012 Oct 5;287(41):34386-99 DOI: 10.1074/jbc.M112.378687 (A collaboration with Hyun Park's lab at the NIH, where we look at the structure and function of the transcription factor Gfi-1)
Adoro, S., McCaughtry, T., Erman, B., Alag, A., Van Laethem, F., Park, JH., Tai, X., Kimura, M., Wang, L., Grinberg, A., Kubo, M., Bosselut, R., Love, P., Singer, A. Coreceptor gene imprinting governs thymocyte lineage fate. EMBO J. 2011 Oct 28;31(2):366-77. doi: 10.1038/emboj.2011.388.
Park, J-H., Adoro, S., Guinter, T., Erman, B., Alag, A., Catalfamo, M., Kimura, M.Y., Cui,Y., Lucas, P.J., Gress, R.E., Kubo, M., Hennighausen, L., Feigenbaum, L., and Singer, A. (2010) Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nature Immunology. Mar;11(3):257-64.
Guimond, M., Veenstra R.G., Grindler, D.J., Zhang, H., Cui, Y., Murphy, R.D., Kim, S.Y., Na, R., Henninghausen, L., Kurtulus, S., Erman, B., Matzinger, P., Merchant, M.S., Mackall, C.L. (2009) IL-7 signaling in dendritic cells regulates CD4+ T cell homeostatic proliferation and CD4+ T cell niche size. Nature Immunology. Feb 10(2):149-157.
Adoro S, Erman B, Sarafova SD, Van Laethem F, Park JH, Feigenbaum L, Singer A. (2008) Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. J Immunol. Nov 15;181 (10):6975-83.
Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A. (2007). 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. Nature Immunology. Oct; 8(10):1049-1059.
Erman, B., Alag, A.S., Dahle, O., van Laethem F., Sarafova, S.D., Guinter, T.I., Sharrow, S.O., Grinberg, A., Love, P.E., and Singer, A. (2006). Coreceptor Signal Strength Regulates Positive Selection but does not Determine CD4/CD8 Lineage Choice in a Physiologic In Vivo Model. Journal of Immunology. 177, 6613 – 6625.
Yu, Q., Park, H., Doan, L., Erman, B., Feigenbaum, L., and Singer, A., (2006) Cytokine signal transduction is suppressed in preselection double positive thymocytes and restored by positive selection. The Journal of Experimental Medicine. 203 (1),165-75.
Sarafova, S., Erman B., Yu, Q., Van Laethem, F., Guinter, T., Sharrow, S., Feigenbaum, L., Wildt, K.F., Bosselut, R., Ellmeier, W. and Singer, A. (2005). Modulation of Coreceptor Transcription During Positive Selection Dictates Lineage Fate Independently of TCR/Coreceptor Specificity. Immunity. 23, 75-87.
Park, J., Yu, Q., Erman, B., Appelbaum, J., Montoya-Durango, D., Grimes, H. L., and Singer, A. (2004). Suppression of IL-7Ra Transcription by IL-7 and other Pro-Survival Cytokines: A Novel Mechanism for Maximizing IL-7 Dependent T cell Survival. Immunity. 21, 289–302.
Yu, Q., Erman, B., Park, J., Feigenbaum, L., and Singer, A. (2004). IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1 and RORgt and Must be Terminated for Thymocyte Differentiation to Proceed. The Journal of Experimental Medicine. 200 (6), 797-803.
Erman, B., Guinter, T., and Singer, A. (2004). Defined ab T Cell Receptors with Distinct Ligand Specificities do not Require Those Ligands to Signal DN Thymocyte Differentiation. The Journal of Experimental Medicine. 199, 1719-1724.
Yu, Q., Erman, B., Bhandoola, A., Sharrow, S.O., and Singer, A. (2003). In Vitro Evidence That Cytokine Receptor Signals Are Required for Differentiation of Double Positive Thymocytes into Functionally Mature CD8+ T Cells. The Journal of Experimental Medicine. 197, 475-487.
Erman, B., Feigenbaum, L., Coligan, J.E., and Singer, A. (2002). Early TCRa expression generates TCRag complexes that signal the DN-to-DP transition and impair development. Nature Immunology, 3, 564-569.
Tian, G., Erman, B., Ishii, H., Gangopadhyay, S. S. and Sen R. (1999). Transcriptional Activation by ETS and Leucine Zipper-Containing Basic Helix-Loop-Helix Proteins. Molecular and Cellular Biology, 19, 2946-2957.
Erman, B., Cortes, M., Nikolyjczyk, B.S., Speck, N.A., and Sen, R. (1998). ETS-Core binding factor: a common composite motif in antigen receptor gene enhancers. Molecular and Cellular Biology, 18, 1322-1330.
Erman, B., and Sen, R. (1996). Context dependent transactivation domains activate the immunoglobulin m heavy chain enhancer. EMBO Journal, 15, 4665-4675.
Nelsen, B., Tian, G., Erman, B., Gregoire, J., Maki, R., Graves, B., and Sen, R. (1993). Regulation of lymphoid-specific immunoglobulin m heavy chain gene enhancer by ETS-domain proteins. Science, 261, 82-86.
Shenkin, P.S., Erman, B. and Mastrandrea, L.D. (1991). Information-theoretical entropy as a measure of sequence variability. Proteins, 11, 297-313.
DOI: 10.25002/tji.2020.1293 (a review on the molecular biology of this terrible virus)
Piepoli, S. Alt, AO. Atilgan,C. Mancini, EJ. and Erman, B. Structural Analysis of the PATZ1 BTB domain homodimer (2020) Acta Crystallographica Section D. Jun 1;76(Pt 6):581-593. DOI: 10.1107/S2059798320005355 (A part of Sofia Piepoli's PhD project. This paper was selected to be featured on the cover page of this crystallagrophy journal. As far as we know, it is the first structural work from Turkey that has been deposited into the PDB database. We continue to crystallize proteins and solve their structures! This was an excellent collaboration between our lab and those of Canan Atilgan and Erika Mancini at Sussex University in the UK)
Kırımtay K, Selçuk E, Kelle D, Erman B, Karabay A. p53 regulates katanin-p60 promoter in HCT 116 cells. Gene. (2020) Feb 15;727:144241. DOI: 10.1016/j.gene.2019.144241 (We contributed to the work of Arzu Karabay at ITU)
Naba, M.N., Tolay, N., Erman, B, Sayi Yazgan, A. The upregulation of PD-L1 expression by doxorubicin in HCT116 colorectal cancer cells accompanied by reduction of miR-140 expression (2019) Turkish Journal of Biology DOI: 10.3906/biy-1909-12 (We contributed to the work of Noel Naba and Ayca Sayi Yazgan at ITU)
Ozyerli-Goknar E, Sur-Erdem I, Seker F, Cingöz A, Kayabolen A, Kahya Z, Uyulur F, Gezen M, Tolay, N, Erman B, Gönen M, Oppermann U, Bagci-Onder T, The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma (2019) Cell Death and Disease, 10, 849. DOI: 10.1038/s41419-019-2107-y (We contributed to the work of Ezgi Ozyerli and Tugba Bagci Onder at Koc University)
Parlar, A., Sayitoglu,EC., Ozkazanc,D., Georgoudaki,A., Pamukcu,C., Aras,M., Josey, BJ., Chrobok,M., Branecki, S., Zahedimaram,P., Ikromzoda,L., Alici,E., Erman,B, Duru,AD, Sutlu, T, Engineering antigen-specific natural killer cells against the melanoma-associated antigen tyrosinase via TCR gene transfer (2019) European Journal of Immunology Aug;49(8):1278-1290. DOI: 10.1002/eji.201948140 (This was an awesome tour de force of biological engineering which resulted in a patent application that is being licenced and will be developed into anti-cancer immunotherapies)
Bonjoch,L. Mur,P. Arnau-Collell,C. Vargas-Parra,G. Shamloo,B. Franch-Expósito, S. Pineda,M. Capellà,G. Erman,B. Castellví-Bel,S. Approaches To Functionally Validate Candidate Genetic Variants Involved In Colorectal Cancer Predisposition (2019) Molecular Aspects of Medicine Special Issue: New insights on the molecular aspects of colorectal cancer. DOI: 10.1016/j.mam.2019.03.004 (A review paper)
Nadernezhad, A. Caliskan, O.S. Topuz,F. Afghah,F. Erman,B. and Koc,B. Nanocomposite Bioinks Based on Agarose and 2D Nanosilicates with Tunable Flow Properties and Bioactivity for 3D Bioprinting (2019) ACS Appl. Bio Mater., 2 (2), pp 796–806 DOI: 10.1021/acsabm.8b00665 (We contributed to the work of Bahattin Koc at Sabanci University)
Etzensperger R, Kadakia T, Tai X, Alag A, Guinter TI, Egawa T, Erman B, Singer A. Identification of lineage-specifying cytokines that signal all CD8+-cytotoxic-lineage-fate 'decisions' in the thymus. (2017) Nat Immunol. Sep 25. doi: 10.1038/ni.3847. (A paper from my post-doctoral laboratory at the NIH)
Deniz E, Erman B. Long noncoding RNA (lincRNA), a new paradigm in gene expression control. Funct Integr Genomics. 2017 May;17(2-3):135-143. doi: 10.1007/s10142-016-0524-x. (A review on these molecules which had just been recently discovered back then)
Keskin, N., Deniz, E., Eryilmaz, J., Un, M., Ersahin, T., Cetin Atalay, R., Sakaguchi, S., Ellmeier, W. and Erman, B. PATZ1 is a DNA damage responsive alternatively spliced heterodimeric transcription factor that inhibits p53 function Molecular and Cellular Biology, 2015 May;35(10):1741-53. doi: 10.1128/MCB.01475-14. (A part of Emre Deniz and Nazli Keskin's PhD projects. Our paper on the molecular mechanism of Patz1 dependent gene transcription is the first output. This project is the major project in our laboratory)
Shamloo, B., and Erman, B. Immune Receptors and Signal Transduction: T and B cell receptors (Immun reseptorler ve sinyal iletimi: T ve B hucre reseptorleri) in Infection Pathogenesis and Immunity (Enfeksiyon Patogenezi ve Bağışıklık), (in Turkish) Ed.s Hakan Abacioglu, Selim Badur and Betigül Öngen (2014)
(A review on T cell receptor signalling in Turkish)
Yilancioglu K, Cokol M, Pastirmaci I, Erman B, Cetiner S. Oxidative Stress Is a Mediator for Increased Lipid Accumulation in a Newly Isolated Dunaliella salina Strain. PLoS ONE 2014 9(3): e91957. doi:10.1371/journal.pone.0091957 (One of the most cited papers with our contribution of staining lipid droplets in algae cells using flow cytometry, thanks Kaan!)
Tai,X., Erman, B., Alag. A., Mu J., Kimura M., Katz G., Guinter, T., McCaughtry, T., Etzensperger, R., Feigenbaum, L., Singer, D.S. and Singer, A. Foxp3 is pro-apoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals. Immunity, 2013, Jun 27;38(6):1116-28. DOI: 10.1016/j.immuni.2013.02.022.
Atasever Arslan B, Erdem-Kuruca S, Karakas Z, Erman B, Ergen A. Effects of micro environmental factors on natural killer activity (NK) of beta thalassemia major patients. Cell Immunol. 2013 Apr;282(2):93-9. DOI: 10.1016/j.cellimm.2013.04.012.
Cevik, S.I., Keskin, N., Deniz, E., Belkaya,S., Ozlu, M.I., Tazebay,U.H., Erman, B. CD81 interacts with the T cell receptor to suppress signaling. PLoS ONE, 2012, 7(11): e50396. DOI:10.1371/journal.pone.0050396 (A part of Isil Cevik's PhD thesis, we performed yeast two hybrid assays and found many molecules that interact with the TCR. We have so many more clones that need to be analyzed).
McCaughtry,T.M., Etzensperger, R., Alag, A., Tai, X., Kurtulus, S., Park, J-H., Grinberg,A. Love, P., Feigenbaum, L., Erman, B., Singer, A. Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus. Journal of Experimental Medicine, 2012, Nov 19;209(12):2263-76. DOI: 10.1084/jem.20121505
Ligons,D.L., Tuncer, C., Linowes, B.A., Akcay, I.M., Kurtulus, S., Deniz, E., Atasever Arslan, B., Cevik, S.I., Keller, H.R., Luckey, M.A., Feigenbaum, L., Möröy,T., Ersahin, T., Atalay, R. and Erman, B., Park, J-H. CD8 Lineage-specific Regulation of Interleukin-7 Receptor Expression by the Transcriptional Repressor Gfi1. Journal of Biological Chemistry. 2012 Oct 5;287(41):34386-99 DOI: 10.1074/jbc.M112.378687 (A collaboration with Hyun Park's lab at the NIH, where we look at the structure and function of the transcription factor Gfi-1)
Adoro, S., McCaughtry, T., Erman, B., Alag, A., Van Laethem, F., Park, JH., Tai, X., Kimura, M., Wang, L., Grinberg, A., Kubo, M., Bosselut, R., Love, P., Singer, A. Coreceptor gene imprinting governs thymocyte lineage fate. EMBO J. 2011 Oct 28;31(2):366-77. doi: 10.1038/emboj.2011.388.
Park, J-H., Adoro, S., Guinter, T., Erman, B., Alag, A., Catalfamo, M., Kimura, M.Y., Cui,Y., Lucas, P.J., Gress, R.E., Kubo, M., Hennighausen, L., Feigenbaum, L., and Singer, A. (2010) Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nature Immunology. Mar;11(3):257-64.
Guimond, M., Veenstra R.G., Grindler, D.J., Zhang, H., Cui, Y., Murphy, R.D., Kim, S.Y., Na, R., Henninghausen, L., Kurtulus, S., Erman, B., Matzinger, P., Merchant, M.S., Mackall, C.L. (2009) IL-7 signaling in dendritic cells regulates CD4+ T cell homeostatic proliferation and CD4+ T cell niche size. Nature Immunology. Feb 10(2):149-157.
Adoro S, Erman B, Sarafova SD, Van Laethem F, Park JH, Feigenbaum L, Singer A. (2008) Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. J Immunol. Nov 15;181 (10):6975-83.
Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A. (2007). 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. Nature Immunology. Oct; 8(10):1049-1059.
Erman, B., Alag, A.S., Dahle, O., van Laethem F., Sarafova, S.D., Guinter, T.I., Sharrow, S.O., Grinberg, A., Love, P.E., and Singer, A. (2006). Coreceptor Signal Strength Regulates Positive Selection but does not Determine CD4/CD8 Lineage Choice in a Physiologic In Vivo Model. Journal of Immunology. 177, 6613 – 6625.
Yu, Q., Park, H., Doan, L., Erman, B., Feigenbaum, L., and Singer, A., (2006) Cytokine signal transduction is suppressed in preselection double positive thymocytes and restored by positive selection. The Journal of Experimental Medicine. 203 (1),165-75.
Sarafova, S., Erman B., Yu, Q., Van Laethem, F., Guinter, T., Sharrow, S., Feigenbaum, L., Wildt, K.F., Bosselut, R., Ellmeier, W. and Singer, A. (2005). Modulation of Coreceptor Transcription During Positive Selection Dictates Lineage Fate Independently of TCR/Coreceptor Specificity. Immunity. 23, 75-87.
Park, J., Yu, Q., Erman, B., Appelbaum, J., Montoya-Durango, D., Grimes, H. L., and Singer, A. (2004). Suppression of IL-7Ra Transcription by IL-7 and other Pro-Survival Cytokines: A Novel Mechanism for Maximizing IL-7 Dependent T cell Survival. Immunity. 21, 289–302.
Yu, Q., Erman, B., Park, J., Feigenbaum, L., and Singer, A. (2004). IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1 and RORgt and Must be Terminated for Thymocyte Differentiation to Proceed. The Journal of Experimental Medicine. 200 (6), 797-803.
Erman, B., Guinter, T., and Singer, A. (2004). Defined ab T Cell Receptors with Distinct Ligand Specificities do not Require Those Ligands to Signal DN Thymocyte Differentiation. The Journal of Experimental Medicine. 199, 1719-1724.
Yu, Q., Erman, B., Bhandoola, A., Sharrow, S.O., and Singer, A. (2003). In Vitro Evidence That Cytokine Receptor Signals Are Required for Differentiation of Double Positive Thymocytes into Functionally Mature CD8+ T Cells. The Journal of Experimental Medicine. 197, 475-487.
Erman, B., Feigenbaum, L., Coligan, J.E., and Singer, A. (2002). Early TCRa expression generates TCRag complexes that signal the DN-to-DP transition and impair development. Nature Immunology, 3, 564-569.
Tian, G., Erman, B., Ishii, H., Gangopadhyay, S. S. and Sen R. (1999). Transcriptional Activation by ETS and Leucine Zipper-Containing Basic Helix-Loop-Helix Proteins. Molecular and Cellular Biology, 19, 2946-2957.
Erman, B., Cortes, M., Nikolyjczyk, B.S., Speck, N.A., and Sen, R. (1998). ETS-Core binding factor: a common composite motif in antigen receptor gene enhancers. Molecular and Cellular Biology, 18, 1322-1330.
Erman, B., and Sen, R. (1996). Context dependent transactivation domains activate the immunoglobulin m heavy chain enhancer. EMBO Journal, 15, 4665-4675.
Nelsen, B., Tian, G., Erman, B., Gregoire, J., Maki, R., Graves, B., and Sen, R. (1993). Regulation of lymphoid-specific immunoglobulin m heavy chain gene enhancer by ETS-domain proteins. Science, 261, 82-86.
Shenkin, P.S., Erman, B. and Mastrandrea, L.D. (1991). Information-theoretical entropy as a measure of sequence variability. Proteins, 11, 297-313.